We offer training opportunities for clinical and non-clinical students. Below are all the projects that are or were supported by the Centre with a non-clinical or intercalated studentship or a clinical research fellowship (including studentships from the former Imperial Centre) 


 

 


2024

 

 

Non-clinical studentships

 

  • Exploiting 3D in vitro models to advance diffusion magnetic resonance imaging (MRI) as a probe of cellular and tumour microstructure - Dr Jessica Winfield (Royal Marsden) , Dr Paula Cunnea (Department of Surgery & Cancer, Imperial College London), Professor Simon Robinson and Professor Christina Messiou (Division of Radiotherapy & Imaging, The ICR)

 

  • Morphological phenotyping of the ccRCC TME using Deep Learning and Morphometrics - Professor Samra Turajilic (Division of Clinical Studies, The ICR), Dr Guang Yang (Department of Bioengineering, Imperial College London), and Professor James Larkin (Division of Clinical Studies, The ICR)

 

 

MB-PhD studentships

 

 

  • An artificial intelligence-based approach to identify immunologic predictors of outcome to immunotherapy in hepatocellular cancer using digital pathology - Dr David Pinato (Department of Surgery & Cancer, Imperial College London), Dr Wenjia Bai (Department of Brain Sciences, Imperial College London), and Dr Francesco Mauri (Department of Surgery & Cancer, Imperial College London)

 

  • Remodelling the tumour immune microenvironment in neuroblastoma by inhibiting RNA splicing - Dr Anke Nijhuis (Department of Surgery & Cancer, Imperial College London), Professor Louis Chesler (Division of Clinical Studies, The ICR), and Professor Hector Keun (Department of Surgery & Cancer, Imperial College London)

 

 

  • Understanding the response to treatment in homologous recombination defective breast cancer by functional profiling of circulating tumour cell clusters - Professor Christopher Lord (Division of Breast Cancer Research, The ICR), Dr Sam Au (Department of Bioengineering, Imperial College London), Professor Andrew Tutt and Dr Stephen Pettitt (Division of Breast Cancer Research, The ICR)

 

Clinical research fellowships

 

  • Discovering, developing, and delivering, novel therapeutic strategies for MEK/ERK/RSK activated lethal prostate cancer - Dr Navita Somaiah (Division of Radiotherapy & Imaging, The ICR), Professor Trevor Graham (Division of Molecular Pathology, The ICR), Professor Alan Melcher (Division of Radiotherapy & Imaging, The ICR), Dr Anita Grigoriadis (Division of Breast Cancer Research, The ICR), Dr Tom Lund (Division of Molecular Pathology, The ICR), Dr Luis Zapata Ortiz (Division of Molecular Pathology, The ICR)

 

  • Understanding the impact of radiotherapy on the nodal immune microenvironment and cross-talk with the primary tumour in breast cancer - Dr Adam Sharp (Division of Clinical Studies, The ICR), Professor Udai Banerji (Division of Cancer Therapeutics, The ICR), Professor Johann De Bono (Division of Clinical Studies, The ICR), Dr Jon Welti (Division of Clinical Studies, The ICR), Dr Marco Bezzi (Division of Molecular Pathology, The ICR), Dr Juan Jimenez Vacas (Division of Clinical Studies, The ICR)

 

  • Novel liquid biopsies to guide treatment in recurrent/metastatic head and neck cancer - Dr Ben O'Leary (Division of Radiotherapy & Imaging, The ICR), Professor Jyoti Choudhary (Division of Cancer Biology, The ICR), and Dr Annie Baker (Division of Molecular Pathology, The ICR)

 

  • Immune derived volatile biomarkers in oesophagogastric cancer - Professor Jessica Strid (Department of Immunology and Inflammation, Imperial College London), Professor George Hanna (Department of Surgery & Cancer, Imperial College London) and Dr Sam Au (Department of Bioengineering, Imperial College London)

 

  • Developing transcription inhibitors as a new class of cancer therapeutics - Professor Simak Ali (Department of Surgery & Cancer, Imperial College London) and Professor Laki Buluwela (Department of Surgery & Cancer, Imperial College London)



 

 


2023

 

 

Non Clinical Studentships

 

 

MB-PhD Studentships

 

 

 

 

 

 

 

 


2022

 

 

Non Clinical Studentships

 

  • Development of novel dual-target agents to treat neuroblastoma that combine selective protein degradation with synergistic inhibition - Professor Louis Chesler (ICR, Clinical Studies), Professor Matt Fuchter (Imperial, Chemistry), Professor Hector Keun & Dr Anke Nijhuis (Imperial, Surgery & Cancer) 

     

  • An explant-in-chip platform to study immune-cancer cell interactions and enhance tumour immunogenicity ex vivo: A focus on radiotherapy - Professor Darryl Overby (Imperial, Bioengineering) & Professor Alan Melcher (ICR, Radiotherapy & Imaging)

     

  • Unravelling the role of cancer associated fibroblasts in cancer evolution and drug resistance using microfluidics - Dr Sam Au (Imperial, Bioengineering) & Professor Udai Banerji (ICR, Cancer Therapeutics)

     

MB-PhD Studentships

 

 

 

 

  • Organ-on-chip platforms for investigating the influence of extracellular matrix components on tumour cell invasion from patient-derived lung explants - Dr Sam Au (Imperial, Bioengineering) Dr Paul Huang (ICR, Molecular Pathology).

 

 

 


2021

 

 

Non-clinical studentships

 

  • RNA barcodes for high-dimensional functionalization of cancer heterogeneity - Professor Zoltan Takats (Imperial, Metabolism, Digestion & Reproduction) & Dr Marco Bezzi (ICR, Molecular Pathology).

 

  • Engineering next generation laminin targeted cancer immunotherapy - Dr Paul Huang (ICR, Molecular Pathology) & Dr Jun Ishihara (Imperial, Bioengineering)

 

 

  • Spatial and temporal high resolution quantitative live imaging techniques to determine mechanisms of chromosomal instability and drug resistance in breast cancer patient-derived organoids - Professor Jorge Bernardino de la Serna (Imperial, National Heart & Lung Institute) & Professor Andrew Tutt (ICR, Breast Cancer Research)

 

MB-PhD studentships

 

 

  • Improving endometrial cancer diagnosis via detection of microRNA biomarkers from liquid biopsies: From biomarker discovery to screening test engineering - Dr Sylvain Ladame (Imperial, Bioengineering) & Professor Sadaf Ghaem-Maghami (Imperial, Surgery & Cancer)

 

  • Bioengineering tumor-targeted cytokines or chemotherapy for effective, specific and personalised immunotherapy combinations in pancreatic cancer - Dr Anguraj Sadanandam (ICR, Molecular Pathology) Dr Jun Ishihara (Imperial, Bioengineering)

 


2020

 

 

Non-clinical studentships

 

 

  • Combined functional MRI and super-resolution ultrasound for non-invasive monitoring of tumour blood delivery during breast cancer radiotherapy - Professor Mengxing Tang (Imperial, Bioengineering), Dr Navita Somaiah (ICR, Radiotherapy & Imaging).

 

  • Magnetic Resonance detection of functionalized extracellular vesicles to understand  their role in breast cancer development and metastasis formation - Professor Simon Robinson (ICR, Radiotherapy & Imaging) & Professor Molly Stevens (Imperial, Materials).

 

  • Synthetic lethality driven by N-myristoyltransferase inhibition: a convergence approach to target MYCN-driven childhood cancers - Professor Ed Tate (Imperial, Chemistry) & Professor Louis Chesler (ICR, Clinical Studies).

 

 

 MB-PhD studentships

 

 

 

  • Developing a point-of-care diagnostic technology for ovarian cancer detection - Mr Srdjan Sasso (Imperial, Department of Metabolism, Digestion and Reproduction) & Professor Molly Stevens (Imperial, Materials).

2019

 

 

Non-clinical studentships (ICR-Imperial)

 

  • Microfluidic Based Reactions with [18F]Fluoroform: A Toolbox for Next Generation 18F-Radiolabelled Medicinal Chemistry Compounds - Dr Gabriela Kramer-Marek (ICR, Radiotherapy & Imaging) & Dr Philip Miller (Imperial, Chemistry) 

 

  • Biomechanical activation of pro-metastatic programs in circulating tumour cells by vasculature constriction forces - Professor Chris Bakal (ICR, Cancer Biology) & Dr Sam Au (Imperial, Bioengineering)

 

 

 

  • Understanding systems and molecular mechanisms underlying cancer immunotherapy for the development of precision immunotherapy with informed strategies - Dr Masahiro Ono (Imperial, Life Sciences) & Professor Alan Melcher (ICR, Radiotherapy & Imaging)

 

  • Investigating the roles of the proteasome vs. autophagy, two major protein degradation pathways, in degradation and stabilisation of the proteome of ovarian high-grade serous carcinoma (HGSC) - Professor Jyoti Choudhary (ICR, Cancer Biology) & Dr Tolga Bozkurt (Imperial, Life Sciences)

 

Non-clinical studentships (Imperial)


  • Exploring PARP biology and therapy response via metabolic flux analysis and a novel chemical proteomics workflow - Professor Hector Keun (Imperial, Surgery & Cancer) Professor Ed Tate & Dr Adrian Benito Mauricio (Imperial, Chemistry).

 


2018

 

 

Non-clinical studentships (ICR-Imperial)

 

 

 

  • A chemical proteomic platform to uncover the impact of dynamic protein S-acylation in cancer - Professor Ed Tate (Imperial, Chemistry) & Professor Julian Downward (ICR)

 

  • Ultrasound backscatter assessment of tumour response to radiotherapy using finite element model-based attenuation and diffraction corrections - Dr Emma Harris (ICR, Radiotherapy & Imaging) & Dr Peter Huthwaite  (Imperial, Mechanical Engineering).

 

  • Short-pulse ultrasound delivery of chemotherapeutic agents across the blood-brain barrier for the treatment of paediatric high grade glioma - Professor Gail Ter Haar (ICR, Radiotherapy & Imaging) & Dr James Choi (Imperial, Bioengineering)

 

 

 

Studentships (Imperial)

 

 

 

 

  • Novel adjuvants for antibody-based cancer therapeutics: design, biological characterisation and influence on membrane-protein structure - Dr Doryen Bubeck (Imperial, Life Sciences) & Professor Ed Tate (Imperial, Chemistry)

2017

 

 

Studentships (Imperial)

 

  • Real time precision phenotyping of significant polyps and early colorectal cancers using rapid evaporative ionisation mass spectrometry (REIMS) - Mr James Kinross and Professor Ara Darzi (Imperial, Surgery & Cancer) & Professor Zoltan Takats (Imperial, Metabolism, Digestion & Reproduction)

 

 

  • Optimisation of colorectal cancer screening and prevention: risk factors for proximal colon cancer and screening of a high-risk population - Professor Amanda Cross (Imperial, Surgery & Cancer)

Before 2016

 

 

Studentships (Imperial)

 

  • Investigating lactate metabolism in cancer and its therapeutic implications - Professor Hector Keun and Professor Eric Aboagye (Imperial, Surgery and Cancer)

 

  • Epigenetic mechanisms of breast cancer prevention by the Type II diabetes mellitus agent metformin - Dr  James Flanagan (Imperial, Surgery and Cancer) and Professor Mark Gunter (Imperial, SPH)


  • Novel chemical proteomics approaches to study N-myristoylation and N-terminal methionine excision - Professor Ed Tate (Imperial, Chemistry)

 

  • RSK4 targeting: a new therapeutic strategy against both drug resistance and metastasis in lung cancer - Professor Michael SecklDr Olivier Pardo & Dr Filippo Prischi (Imperial, Surgery and Cancer)

 

  • Understanding the mechanisms of action of estrogen receptor mutations in metastatic breast cancer - Professor Simak Ali and Professor Laki Buluwela (Imperial, Surgery and Cancer)