Our Centre has world-leading capabilities in surgical and radiotherapy technologies, cancer detection, and device technologies. We are at the forefront of developing novel clinical interventions for the benefit of patients. Importantly, generating early evidence on clinical utility, human factors, and cost-effectiveness are key factors in ensuring success, redirecting development, and abandoning unpromising technologies at an early stage.

However, there are several challenges for the adoption of innovations, often associated with bridging the expertise of engineers with the requirements of the healthcare market. We aim to guide our technologies along the adoption pathways. To achieve this, we have established a group of specialists actively supporting clinical positioning and human factors mapping, patient engagement, health economics, and utilising dissemination and implementation sciences.

    Challenges to Implementing Technology in Real-World Clinical Settings

    • Clinical positioning: Often, a technology platform requires careful consideration of its precise clinical application to ensure its development aligns with clinical utility. Alternatively, technologies may need to be adapted from a design intended for a single cancer site to a platform that can be used for multiple cancers. This adaptation aims to increase the technology's acceptance and cost-effectiveness within clinical practice.
    • Clinical trials: To progress through the regulatory pathway, specific datasets are required to support the technology's development. This necessitates the use of novel first-in-human study designs to demonstrate safety before moving on to efficacy-based trials. Additionally, it is necessary to develop prototype devices into clinically implementable technologies, which are required to initiate clinical studies.
    • Implementation: Generating early evidence on human factors and health economic modelling is essential to guide the development of cancer technology towards clinical utility. Understanding how the technology integrates into the existing healthcare system and the impact it has on patient care and outcomes is crucial for successful implementation.


    Doctor treating patient in ward



    Thus, successfully translating novel technologies, devices, and treatments into clinical practice requires a collaborative and multidisciplinary effort to navigate research ethics, regulatory approval processes, and provide the necessary support for optimal clinical positioning. These challenges often pose significant barriers, hindering innovations from attracting external commercial and venture capital funding required for progression to clinical use. To address the challenges outlined above, our team facilitates the translation of the most promising innovations along the clinical approval pathway to maximise the likelihood of clinical adoption.


    To overcome these hurdles and ensure the successful implementation of innovations, we recognise the importance of attracting commercial and industrial partners. These partnerships are vital for scaling up, disseminating, and sustaining innovative technologies beyond the clinical realm. By fostering collaborations with commercial and industrial stakeholders, we aim to create mutually beneficial relationships that drive the adoption and commercialisation of promising innovations. This includes providing support in navigating intellectual property considerations, conducting market analysis, and developing business strategies.