Publications
Publications
Coagulation factor X promotes resistance to androgen-deprivation therapy in prostate cancer - Cancer Cell. 2024 Sep 16:S1535-6108(24)00317-9.
Calì B, Troiani M, Bressan S, Attanasio G, Merler S, Moscarda V, Mosole S, Ricci E, Guo C, Yuan W, Gallagher L, Lundberg A, Bernett I, Figueiredo I, Arzola RA, Abreut EB, D'Ambrosio M, Bancaro N, Brina D, Zumerle S, Pasquini E, Maddalena M, Lai P, Colucci M, Pernigoni N, Rinaldi A, Minardi D, Morlacco A, Moro FD, Sabbadin M, Galuppini F, Fassan M, Rüschoff JH, Moch H, Rescigno P, Francini E, Saieva C, Modesti M, Theurillat JP, Gillessen S, Wilgenbus P, Graf C, Ruf W, de Bono J, Alimonti A.
PoLambRimetry: a multispectral polarimetric atlas of lamb brain - J Biomed Opt. 2024 Sep;29(9):096002.
Mieites V, Anichini G, Qi J, O'Neill K, Conde OM, Elson DS.
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer - Oncogene. 2024 Sep 13. doi: 10.1038/s41388-024-03148-4. Epub ahead of print. PMID: 39266679.
Sardar S, McNair CM, Ravindranath L, Chand SN, Yuan W, Bogdan D, Welti J, Sharp A, Ryan NK, Knudsen LA, Schiewer MJ, DeArment EG, Janas T, Su XA, Butler LM, de Bono JS, Frese K, Brooks N, Pegg N, Knudsen KE, Shafi AA.
BCL2 expression is enriched in advanced prostate cancer with features of lineage plasticity - J Clin Invest. 2024 Sep 17;134(18):e179998.
Westaby D, Jiménez-Vacas JM, Figueiredo I, Rekowski J, Pettinger C, Gurel B, Lundberg A, Bogdan D, Buroni L, Neeb A, Padilha A, Taylor J, Zeng W, Das S, Hobern E, Riisnaes R, Crespo M, Miranda S, Ferreira A, Hanratty BP, Nava Rodrigues D, Bertan C, Seed G, Fenor de La Maza MLD, Guo C, Carmichael J, Grochot R, Chandran K, Stavridi A, Varkaris A, Stylianou N, Hollier BG, Tunariu N, Balk SP, Carreira S, Yuan W, Nelson PS, Corey E, Haffner M, de Bono J, Sharp A.
Recent Electrochemical Advancements for Liquid-Biopsy Nucleic Acid Detection for Point-of-Care Prostate Cancer Diagnostics and Prognostics - Biosensors. 2024; 14(9):443.
Broomfield J, Kalofonou M, Bevan CL, Georgiou P.
YAP activation is robust to dilution - Mol Omics. 2024 Sep 16.
Jones I, Arias-Garcia M, Pascual-Vargas P, Beykou M, Dent L, Chaudhuri TP, Roumeliotis T, Choudhary J, Sero J, Bakal C.
DrugSynthMC: An Atom-Based Generation of Drug-like Molecules with Monte Carlo Search - J Chem Inf Model. 2024 Sep 9.
Roucairol M, Georgiou A, Cazenave T, Prischi F, Pardo OE.
Super-resolved fluorescence imaging utilising accessible stochastic optical reconstruction microscopy (easySTORM) implemented on a low-cost, modular open-source (openFrame) microscope - Measurement Science and Technology. 2024 Sept 2.
Anupam Bharadwaj, Amalesh Kumar, Ranjan Kalita, Rumela Mitra, Amit Sharma, Bithiah G. Jaganathan, Jina Bhattacharyya, Anupam Sarma, Edwin Garcia, Bosanta R. Boruah, Sunil Kumar, Jonathon Lightley, Yuriy Alexandrov, Christopher Dunsby, Mark Neil, and Paul M. W. French
GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant - Cancer Cell. 2024 Aug 27:S1535-6108(24)00305-2.
Liu I, Alencastro Veiga Cruzeiro G, Bjerke L, Rogers RF, Grabovska Y, Beck A, Mackay A, Barron T, Hack OA, Quezada MA, Molinari V, Shaw ML, Perez-Somarriba M, Temelso S, Raynaud F, Ruddle R, Panditharatna E, Englinger B, Mire HM, Jiang L, Nascimento A, LaBelle J, Haase R, Rozowsky J, Neyazi S, Baumgartner AC, Castellani S, Hoffman SE, Cameron A, Morrow M, Nguyen QD, Pericoli G, Madlener S, Mayr L, Dorfer C, Geyeregger R, Rota C, Ricken G, Ligon KL, Alexandrescu S, Cartaxo RT, Lau B, Uphadhyaya S, Koschmann C, Braun E, Danan-Gotthold M, Hu L, Siletti K, Sundström E, Hodge R, Lein E, Agnihotri S, Eisenstat DD, Stapleton S, King A, Bleil C, Mastronuzzi A, Cole KA, Waanders AJ, Montero Carcaboso A, Schüller U, Hargrave D, Vinci M, Carceller F, Haberler C, Slavc I, Linnarsson S, Gojo J, Monje M, Jones C, Filbin MG.
A Topological Gaussian Mixture Model for Bone Marrow Morphology in Leukaemia - Arxiv [Preprint]. 24 Aug 2024.
Qiquan Wang, Anna Song, Antoniana Batsivari, Dominique Bonnet, Anthea Monod
Technologies and techniques to improve precision in breast conserving surgery - J Surg Oncol. 2024 Aug 21.
Pitfalls and challenges of peptide nucleic acid immobilisation on carbon surfaces for sequence-specific capturing of nucleic acid biomarkers - Biosens Bioelectron. 2024 Aug 3;264:116634.
Meng X, Petrou L, Kenaan A, Khan D, O'Hare D, Ladame S.
Commentary: The North West London Clinical Trials Alliance: efficiency and innovation in clinical trial delivery - Trials. 2024 Jul 29;25(1):509.
Kierkegaard P, Su B, Wong R, Boffito M, Balendra S.
Injectable conductive hydrogel electrodes for minimally invasive neural interfaces - J. Mater. Chem. B, 2024.
Kusen Ines; Lee, Aaron; Cuttaz, Estelle; Bailey, Zachary K; Killilea, Joshua; Merlo-Nikpay Aslie, Shirine; Goding, Josef; Green, Rylie.
Prospective Study of Non-Contrast, Abbreviated MRI for Hepatocellular Carcinoma Surveillance in Patients with Suboptimal Hepatic Visualisation on Ultrasound - Cancers. 2024; 16(15):2709.
Vithayathil M, Qurashi M, Vicente PR, Alsafi A, Naik M, Graham A, Khan S, Lewis H, Dhar A, Smith B, Selvapatt N, Manousou P, Possamai L, Izadi H, Lim A, Tait P, Sharma R.
Stability for Inference with Persistent Homology Rank Functions - Computer Graphics Forum, 43: e15142.
Wang, Q., García-Redondo, I., Faugère, P., Henselman-Petrusek, G. and Monod, A.
Opportunities and Challenges in Soft Tissue Sarcoma Risk Stratification in the Era of Personalised Medicine - Curr Treat Options Oncol. 2024 Jul 30.
Chowdhury A, Thway K, Pasquali S, Callegaro D, Gronchi A, Jones RL, Huang PH.
A novel Nav1.5-dependent feedback mechanism driving glycolytic acidification in breast cancer metastasis - Oncogene. 2024 Jul 25.
Leslie TK, Tripp A, James AD, Fraser SP, Nelson M, Sajjaboontawee N, Capatina AL, Toss M, Fadhil W, Salvage SC, Garcia MA, Beykou M, Rakha E, Speirs V, Bakal C, Poulogiannis G, Djamgoz MBA, Jackson AP, Matthews HR, Huang CL, Holding AN, Chawla S, Brackenbury WJ.
Synthesis and Functionalization of Biodegradable Second Harmonic Generation Nanoprobes for Cell Targeting - Curr Protoc. 2024 Jul;4(7):e1089. doi: 10.1002/cpz1.1089. PMID: 39034855.
Ulucay E, Bollier P, Spilioti M, Sonay AY, Kalyviotis K, Pantazis P.
Simulation of ultrasound backscatter coefficient measurement using the finite element method - Ultrasonics. July 2024,107394, ISSN 0041-624X.
George West, Stewart Haslinger, Jeffrey Bamber, Michael Lowe, Peter Huthwaite, Emma Harris
Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer - Nat Cancer. 2024 Jul 12. doi: 10.1038/s43018-024-00787-0. Epub ahead of print. PMID: 38997466.
Fernandez-Mateos J, Cresswell GD, Trahearn N, Webb K, Sakr C, Lampis A, Stuttle C, Corbishley CM, Stavrinides V, Zapata L, Spiteri I, Heide T, Gallagher L, James C, Ramazzotti D, Gao A, Kote-Jarai Z, Acar A, Truelove L, Proszek P, Murray J, Reid A, Wilkins A, Hubank M, Eeles R, Dearnaley D, Sottoriva A.
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance - Nature. 2024 Jul 3.
Chen H, Li Y, Li H, Chen X, Fu H, Mao D, Chen W, Lan L, Wang C, Hu K, Li J, Zhu C, Evans I, Cheung E, Lu D, He Y, Behrens A*, Yin D*, Zhang C*.
The genomic trajectory of ovarian high-grade serous carcinoma can be observed in STIC lesions - J Pathol. 2024 Jul 2.
Cheng Z, Ennis DP, Lu B, Mirza HB, Sokota C, Kaur B, Singh N, Le Saux O, Russo G, Giannone G, Tookman LA, Krell J, Barnes C, McDermott J, McNeish IA.
Microbial signatures and continuum in endometrial cancer and benign patients - Microbiome. 2024 Jul 1;12(1):118.
Semertzidou A, Whelan E, Smith A, Ng S, Roberts L, Brosens JJ, Marchesi JR, Bennett PR, MacIntyre DA, Kyrgiou M.
A geometric approach to robust medical image segmentation - Med Image Anal. 2024 Jun 29;97:103260.
Santhirasekaram A, Winkler M, Rockall A, Glocker B.
On the Limitations of Fractal Dimension as a Measure of Generalization - Arxiv [Preprint]. 4 Jun 2024.
Charlie Tan, Inés García-Redondo, Qiquan Wang, Michael M. Bronstein, Anthea Monod
Logistic Variational Bayes Revisited - Arxiv [Preprint]. 2 Jun 2024.
Michael Komodromos, Marina Evangelou, Sarah Filippi
G-quadruplex structures regulate long-range transcriptional reprogramming to promote drug resistance in ovarian cancer - bioRxiv [Preprint]. 2024 June 28:2024. 06. 24 .600010.
Jenna Robinson*, Gem Flint*, Ian Garner, Silvia Galli, Thomas E. Maher, Marina K. Kuimova, Ramon Vilar, Iain A. McNeish, Robert Brown, Hector Keun, Marco Di Antonio
Evaluating prostate cancer bone metastases response with whole-body MRI: What we know and still need to know - Eur Radiol. 2024 Jun 20.
Padhani AR, Tunariu N, Perez-Lopez R, Tombal B, Lecouvet FE.
Nuclear rupture induced by capillary constriction forces promotes differential effects on metastatic and normal breast cells - Sci Rep. 2024 Jun 26;14(1):14793.
Perea Paizal J, Au SH, Bakal C
Stereotactic Body Radiotherapy for Oligoprogression in Castration-Resistant Prostate Cancer: Early Toxicity Analysis of the TRAP Trial - Clin Oncol (R Coll Radiol). 2024 Jun.
Patel PH, Dreibe S, Reid A, Parker C, Murray J, Pathmanathan A, Tirona A, Guevara J, Suh YE, Frew J, Palaniappan N, Syndikus I, Attard G, Tunariu N, Tree AC.
Multispectral Mueller matrix imaging: a potential tool to visualize white matter tracts - Proc. SPIE 13010, Tissue Optics and Photonics III, 130100G (18 June 2024).
Verónica Mieites, Giulio Anichini, Ji Qi, Kevin O'Neill, Olga M. Conde, and Daniel S. Elson
Biocompatibility characterisation of CMOS-based Lab-on-Chip electrochemical sensors for in vitro cancer cell culture applications - Biosensors and Bioelectronics 262 (2024) 116513.
Melina Beykou, Vicky Bousgouni, Nicolas Moser, Pantelis Georgiou, Chris Bakal
Description of subgroup reporting in clinical trials of chronic diseases: a meta-epidemiological study - BMJ Open. 2024 Jun 21;14(6):e081315.
Wei L, Butterly E, Rodríguez Pérez J, Chowdhury A, Shemilt R, Hanlon P, McAllister D.
Capturing longer term surgical outcome measures as part of routine care of breast cancer patients - Breast. 2024 Jun 5;76:103758.
Leusink AE, Godden AR, Yildirim N, Randawa A, Law R, Rusby JE.
RNASEH2B loss and PARP inhibition in advanced prostate cancer - J Clin Invest. 2024 Jun 4:e178278.
Carmichael J, Figueiredo I, Gurel B, Beije N, Yuan W, Rekowski J, Seed G, Carreira S, Bertan C, Fenor de la Maza MLD, Chandran K, Neeb A, Welti J, Gallagher L, Bogdan D, Crespo M, Riisnaes R, Ferreira A, Miranda S, Lu J, Shen MM, Hall E, Porta N, Westaby D, Guo C, Grochot R, Lord CJ, Mateo J, Sharp A, de Bono J.
Optical projection tomography implemented for accessibility and low cost (OPTImAL) - Philos Trans A Math Phys Eng Sci. 2024 Jul 9;382(2274):20230101.
Darling C, Kumar S, Alexandrov Y, de Faye J, Almagro Santiago J, Rýdlová A, Bugeon L, Dallman MJ, Behrens AJ, French PMW, McGinty J.
How Do Patients Use Self-Care to Manage Nonspecific Symptoms Prior to a Cancer Diagnosis? A Rapid Review to Inform Future Interventions to Reduce Delays in Presentation to Primary Care - European Journal of Cancer Care, vol. 2024, Article ID 5580195, 15 pages, 2024.
Georgia Wilson, Hannah R. Brewer, James M. Flanagan, Christian von Wagner, Yasemin Hirst.
Pseudomembranous colitis and Parabacteroides distasonis bacteraemia: a rare clinical presentation - Clin J Gastroenterol. 2024 Jun;17(3):457-460.
Hsu C, Moore-Gillon C, Vithayathil M, Karim S.
Chemical tools for profiling the intracellular ADP-ribosylated proteome - RSC Chem Biol. 2024 May 22;5(7):640-651.
Draganov SD, Gruet MJ, Conole D, Balcells C, Siskos AP, Keun HC, Haskard DO, Tate EW.
A functional survey of the regulatory landscape of estrogen-receptor-positive breast cancer evolution - Cancer Discov. 2024 May 16.
Barozzi I, Slaven N, Canale E, Lopes R, Amorim Monteiro Barbosa I, Bleu M, Ivanoiu D, Pacini C, Mensa E, Chambers A, Bravaccini S, Ravaioli S, Gyorffy B, Dieci MV, Pruneri G, Galli GG, Magnani L.
Clinical implications and molecular features of extracellular matrix networks in soft tissue sarcomas - Clin Cancer Res. 2024 May 29.
Pankova V, Krasny L, Kerrison W, Tam YB, Chadha M, Burns J, Wilding CP, Chen L, Chowdhury A, Perkins E, Lee ATJ, Howell L, Guljar N, Sisley K, Fisher C, Chudasama P, Thway K, Jones RL, Huang PH.
Secretome of Cancer-Associated Fibroblasts (CAFs) Influences Drug Sensitivity in Cancer Cells - J Proteome Res. 2024 May 20.
Lau R, Yu L, Roumeliotis TI, Stewart A, Pickard L, Choudhary JS, Banerji U.
Robust prostate disease classification using transformers with discrete representations - Int J Comput Assist Radiol Surg. 2024 May 13.
Santhirasekaram A, Winkler M, Rockall A, Glocker B.
Repeat it without me: Crowdsourcing the T1 mapping common ground via the ISMRM reproducibility challenge - Magn Reson Med. 2024 May 10.
Boudreau M, Karakuzu A, Cohen-Adad J, Bozkurt E, Carr M, Castellaro M, Concha L, Doneva M, Dual SA, Ensworth A, Foias A, Fortier V, Gabr RE, Gilbert G, Glide-Hurst CK, Grech-Sollars M, Hu S, Jalnefjord O, Jovicich J, Keskin K, Koken P, Kolokotronis A, Kukran S, Lee NG, Levesque IR, Li B, Ma D, Mädler B, Maforo NG, Near J, Pasaye E, Ramirez-Manzanares A, Statton B, Stehning C, Tambalo S, Tian Y, Wang C, Weiss K, Zakariaei N, Zhang S, Zhao Z, Stikov N; ISMRM Reproducible Research Study Group and the ISMRM Quantitative MR Study Group.
AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer - bioRxiv [Preprint]. 2024 May 7:2024.05.07.592966.
Sardar S, McNair CM, Ravindranath L, Chand SN, Yuan W, Bogdan D, Welti J, Sharp A, Ryan NK, Schiewer MJ, DeArment EG, Janas T, Su XA, Butler LM, de Bono JS, Frese K, Brooks N, Pegg N, Knudsen KE, Shafi AA.
Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer - Br J Cancer. 2024 May;130(11):1828-1840.
Alexander J, Schipper K, Nash S, Brough R, Kemp H, Iacovacci J, Isacke C, Natrajan R, Sawyer E, Lord CJ, Haider S. .
Shining a spotlight on the inclusion of disabled participants in clinical trials: a mixed methods study - Trials. 2024 Apr 26;25(1):281.
Sakuma Y, Miller MLE, Babalis DS, Baker A, Reddi M, Anjum A, Bruton J, Jones KN, Mulla UZ, Taddese H.
Circulating tumor cells shed large extracellular vesicles in capillary-sized bifurcations - BioRxiv. April 20, 2024.
Angelos Vrynas, Sara Arfan, Karishma Satia, Salime Bazban-Shotorbani, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au
Serial Postoperative Circulating Tumor DNA Assessment Has Strong Prognostic Value During Long-Term Follow-Up in Patients With Breast Cancer - JCO Precis Oncol. 2024 Apr;8:e2300456.
Shaw JA, Page K, Wren E, de Bruin EC, Kalashnikova E, Hastings R, McEwen R, Zhang E, Wadsley M, Acheampong E, Renner D, Gleason KLT, Ambasager B, Stetson D, Fernandez-Garcia D, Guttery D, Allsopp RC, Rodriguez A, Zimmermann B, Sethi H, Aleshin A, Liu MC, Richards C, Stebbing J, Ali S, Rehman F, Cleator S, Kenny L, Ahmed S, Armstrong AC, Coombes RC.
The Lancet Commission on prostate cancer: planning for the surge in cases - Lancet. 2024 Apr 4:S0140-6736(24)00651-2
James ND, Tannock I, N'Dow J, Feng F, Gillessen S, Ali SA, Trujillo B, Al-Lazikani B, Attard G, Bray F, Compérat E, Eeles R, Fatiregun O, Grist E, Halabi S, Haran Á, Herchenhorn D, Hofman M, Jalloh M, Loeb S, MacNair A, Mahal B, Mendes L, Moghul M, Moore C, Morgans A, Morris M, Murphy D, Murthy V, Nguyen PL, Padhani A, Parker C, Rush H, Sculpher M, Soule H, Sydes MR, Tilki D, Tunariu N, Villanti P, Xie LP.
CB307: A Dual Targeting Costimulatory Humabody VH Therapeutic for Treating PSMA-Positive Tumors - Clin Cancer Res. 2024 Apr 9:OF1-OF12.
Archer S, Brailey PM, Song M, Bartlett PD, Figueiredo I, Gurel B, Guo C, Brucklacher-Waldert V, Thompson HL, Akinwale J, Boyle SE, Rossant C, Birkett NR, Pizzey J, Maginn M, Legg J, Williams R, Johnston CM, Bland-Ward P, de Bono JS, Pierce AJ.
Validated machine learning tools to distinguish immune checkpoint inhibitor, radiotherapy, COVID-19 and other infective pneumonitis - Radiother Oncol. 2024 Apr 4:195:110266.
Hindocha S, Hunter B, Linton-Reid K, George Charlton T, Chen M, Logan A, Ahmed M, Locke I, Sharma B, Doran S, Orton M, Bunce C, Power D, Ahmad S, Chan K, Ng P, Toshner R, Yasar B, Conibear J, Murphy R, Newsom-Davis T, Goodley P, Evison M, Yousaf N, Bitar G, McDonald F, Blackledge M, Aboagye E, Lee R.
Characterizing functional DNA damage and response caused by the combination of CHK1 and WEE1 inhibitors in ovarian and breast cancer models - BJC Rep 2, 27 (2024).
Adam Stewart, Jiin Song, Lisa Pickard, Giovanna Muggiolu, Sylvie Sauvaigo, Alexis De Haven Brandon, Florence Raynaud & Udai Banerji
Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells - Cancer Discov. 2024 Mar 21:OF1-OF24.
Dalia Rosano, Emre Sofyali, Heena Dhiman, Chiara Ghirardi, Diana Ivanoiu, Timon Heide, Andrea Vingiani, Alessia Bertolotti, Giancarlo Pruneri, Eleonora Canale, Hannah F Dewhurst, Debjani Saha, Neil Slaven, Iros Barozzi, Tong Li, Grigory Zemlyanskiy, Henry Phillips, Chela James, Balázs Győrffy, Claire Lynn, George D Cresswell, Farah Rehman, Roberta Noberini, Tiziana Bonaldi, Andrea Sottoriva, Luca Magnani
Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30 - RSC Chem Biol, 2024, Advance Article.
Milon Mondal, Fangyuan Cao, Daniel Conole, Holger W. Auner and Edward W. Tate.
Genome-wide mapping of G-quadruplex DNA: a step-by-step guide to select the most effective method - RSC Chem Biol, 2024, Advance Article.
Silvia Galli, Gem Flint, Lucie Růžičková and Marco Di Antonio
Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity - Nat Rev Cancer. 2024 Mar 7.
Pascal Meier, Arnaud J. Legrand, Dieter Adam & John Silke
Protein lipidation in cancer: mechanisms, dysregulation and emerging drug targets - Nat Rev Cancer. 2024 Feb 29.
Edward W. Tate, Lior Soday, Ana Losada de la Lastra, Mei Wang & Hening Lin
Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer - Mol Cancer Ther. 2024 Feb 27.
Antje Neeb, Ines Figueiredo, Denisa Bogdan, Laura Cato, Jutta Stober, Juan M Jiménez-Vacas, Victor Gourain, Irene I Lee, Rebecca Seeger, Claudia Muhle-Goll, Bora Gurel, Jonathan Welti, Daniel Nava Rodrigues, Jan Rekowski, Xintao Qiu, Yija Jiang, Patrizio Di Micco, Borja Mateos, Stasė Bielskutė, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Mateus Crespo, Lorenzo Buroni, Jian Ning, Suzanne Carreira, Stefan Bräse, Nicole Jung, Simone Gräßle, Amanda Swain, Xavier Salvatella, Stephen R Plymate, Bissan Al-Lazikani, Henry W Long, Wei Yuan, Myles Brown, Andrew C B Cato, Johann S de Bono, Adam Sharp
A first-in-human phase I study of the PD-1 inhibitor, retifanlimab (INCMGA00012), in patients with advanced solid tumors (POD1UM-101) - ESMO Open. 2024 Feb 21;9(4):102254.
Lakhani N, Cosman R, Banerji U, Rasco D, Tomaszewska-Kiecana M, Garralda E, Kornacki D, Li J, Tian C, Bourayou N, Powderly J.
Circulating microRNA analysis in a prospective co-clinical trial identifies MIR652-3p as a response biomarker and driver of regorafenib resistance mechanisms in colorectal cancer - Clin Cancer Res. 2024 Feb 20.
Fiberbots: Robotic fibers for high-precision minimally invasive surgery - Sci Adv. 2024 Jan 19;10(3):eadj1984.
Mohamed E.M.K. Abdelaziz, Jinshi Zhao, Bruno Gil Rosa, Hyun-Taek Lee, Daniel Simon, Khushi Vyas, Bing Li, Hanifa Koguna, Yue Li, Ali Anil Demircali, Huseyin Uvet, Gulsum Gencoglan, Arzu Akcay, Mohamed Elriedy, James Kinross, Ranan Dasgupta, Zoltan Takats, Eric Yeatman, Guang-Zhong Yang, Burak Temelkuran
Deep Learning for Delineation of the Spinal Canal in Whole-Body Diffusion-Weighted Imaging: Normalising Inter- and Intra-Patient Intensity Signal in Multi-Centre Datasets - Bioengineering (Basel). 2024 Jan 29;11(2):130.
Antonio Candito, Richard Holbrey, Ana Ribeiro, Christina Messiou, Nina Tunariu, Dow-Mu Koh, Matthew D Blackledge
Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase - J Med Chem. 2024 Jan 25;67(2):1061-1078.
Markus Ritzefeld, Leran Zhang, Zhangping Xiao, Sebastian A. Andrei, Olivia Boyd, Naoko Masumoto, Ursula R. Rodgers, Markus Artelsmair, Lea Sefer, Angela Hayes, Efthymios-Spyridon Gavriil, Florence I. Raynaud, Rosemary Burke, Julian Blagg, Henry S. Rzepa, Christian Siebold, Anthony I. Magee, Thomas Lanyon-Hogg, and Edward W. Tate
Real-time classification of tumour and non-tumour tissue in colorectal cancer using diffuse reflectance spectroscopy and neural networks to aid margin assessment - Int J Surg. 2024 Jan 22.
Scarlet Nazarian, Ioannis Gkouzionis, Jamie Murphy, Ara Darzi, Nisha Patel, Christopher J Peters, Daniel S Elson
A palmitoyl transferase chemical–genetic system to map ZDHHC-specific S-acylation - Nat Biotechnol. 2024 Jan 8.
Cory A. Ocasio, Marc P. Baggelaar, James Sipthorp, Ana Losada de la Lastra, Manuel Tavares, Jana Volarić, Christelle Soudy, Elisabeth M. Storck, Jack W. Houghton, Susana A. Palma-Duran, James I. MacRae, Goran Tomić, Lotte Carr, Julian Downward, Ulrike S. Eggert & Edward W. Tate
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation - J Clin Invest. 2024 Jan 16;134(2):e175369.
Magnus T Dillon, Jeane Guevara, Kabir Mohammed, Emmanuel C Patin, Simon A Smith, Emma Dean, Gemma N Jones, Sophie E Willis, Marcella Petrone, Carlos Silva, Khin Thway, Catey Bunce, Ioannis Roxanis, Pablo Nenclares, Anna Wilkins, Martin McLaughlin, Adoracion Jayme-Laiche, Sarah Benafif, Georgios Nintos, Vineet Kwatra, Lorna Grove, David Mansfield, Paula Proszek, Philip Martin, Luiza Moore, Karen E Swales, Udai Banerji, Mark P Saunders, James Spicer, Martin D Forster, Kevin J Harrington
Exposure to Aldehyde Cherry e-Liquid Flavoring and Its Vaping Byproduct Disrupt Pulmonary Surfactant Biophysical Function - Environ Sci Technol. 2024 Jan 8.
Alexia Martin, Carmelo Tempra, Yuefan Yu, Juho Liekkinen, Roma Thakker, Hayoung Lee, Berta de Santos Moreno, Ilpo Vattulainen, Christos Rossios, Matti Javanainen, Jorge Bernardino de la Serna
O-RADS MRI scoring system has the potential to reduce the frequency of avoidable adnexal surgery - Eur J Obstet Gynecol Reprod Biol. 2024 Jan 17:294:135-142.
Yohann Dabi, Andrea Rockall, Léo Razakamanantsoa, Adalgisa Guerra, Laure S Fournier, Christina Fotopoulou, Cyril Touboul, Isabelle Thomassin-Naggara; Eurad Study Group
2023
Optimizing the FDA's Project Optimus: opportunities and challenges - Nat Rev Clin Oncol. 2023 Dec 21.
Simon Rodney & Udai Banerji
Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer: A Diagnostic Test Accuracy Study - Invest Radiol. 2023 Dec 1;58(12):823-831.
Rockall AG, Li X, Johnson N, Lavdas I, Santhakumaran S, Prevost AT, Punwani S, Goh V, Barwick TD, Bharwani N, Sandhu A, Sidhu H, Plumb A, Burn J, Fagan A, Wengert GJ, Koh DM, Reczko K, Dou Q, Warwick J, Liu X, Messiou C, Tunariu N, Boavida P, Soneji N, Johnston EW, Kelly-Morland C, De Paepe KN, Sokhi H, Wallitt K, Lakhani A, Russell J, Salib M, Vinnicombe S, Haq A, Aboagye EO, Taylor S, Glocker B.
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation - J Clin Invest. 2023 Nov 7:e175369.
Dillon MT, Guevara J, Mohammed K, Patin EC, Smith SA, Dean E, Jones GN, Willis SE, Petrone M, Silva C, Thway K, Bunce C, Roxanis I, Nenclares P, Wilkins A, McLaughlin M, Jayme-Laiche A, Benafif S, Nintos G, Kwatra V, Grove L, Mansfield DC, Proszek P, Martin P, Moore L, Swales KE, Banerji U, Saunders MP, Spicer J, Forster MD, Harrington KJ.
The effect of nodal connectivity and strut density within stochastic titanium scaffolds on osteogenesis - Front Bioeng Biotechnol. 2023 Nov 29:11:1305936.
Stylianos Kechagias, Konstantinos Theodoridis, Joseph Broomfield, Kenny Malpartida-Cardenas, Ruth Reid, Pantelis Georgiou, Richard J van Arkel, Jonathan R T Jeffers
Repeatability of quantitative individual lesion and total disease multiparametric whole-body MRI measurements in prostate cancer bone metastases - Br J Radiol. 2023 Nov;96(1151):20230378.
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