Publications
Publications
2023
Development and Evaluation of Machine Learning in Whole-Body Magnetic Resonance Imaging for Detecting Metastases in Patients With Lung or Colon Cancer: A Diagnostic Test Accuracy Study - Invest Radiol. 2023 Dec 1;58(12):823-831.
Rockall AG, Li X, Johnson N, Lavdas I, Santhakumaran S, Prevost AT, Punwani S, Goh V, Barwick TD, Bharwani N, Sandhu A, Sidhu H, Plumb A, Burn J, Fagan A, Wengert GJ, Koh DM, Reczko K, Dou Q, Warwick J, Liu X, Messiou C, Tunariu N, Boavida P, Soneji N, Johnston EW, Kelly-Morland C, De Paepe KN, Sokhi H, Wallitt K, Lakhani A, Russell J, Salib M, Vinnicombe S, Haq A, Aboagye EO, Taylor S, Glocker B.
Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation - J Clin Invest. 2023 Nov 7:e175369.
Dillon MT, Guevara J, Mohammed K, Patin EC, Smith SA, Dean E, Jones GN, Willis SE, Petrone M, Silva C, Thway K, Bunce C, Roxanis I, Nenclares P, Wilkins A, McLaughlin M, Jayme-Laiche A, Benafif S, Nintos G, Kwatra V, Grove L, Mansfield DC, Proszek P, Martin P, Moore L, Swales KE, Banerji U, Saunders MP, Spicer J, Forster MD, Harrington KJ.
Repeatability of quantitative individual lesion and total disease multiparametric whole-body MRI measurements in prostate cancer bone metastases - Br J Radiol. 2023 Nov;96(1151):20230378.
Donners R, Candito A, Blackledge M, Rata M, Messiou C, Koh DM, Tunariu N.
Radiomics-based decision support tool assists radiologists in small lung nodule classification and improves lung cancer early diagnosis - Br J Cancer. 2023 Nov 6.
Benjamin Hunter, Christos Argyros, Marianna Inglese, Kristofer Linton-Reid, Ilaria Pulzato, Andrew G. Nicholson, Samuel V. Kemp, Pallav L. Shah, Philip L. Molyneaux, Cillian McNamara, Toby Burn, Emily Guilhem, Marcos Mestas Nuñez, Julia Hine, Anika Choraria, Prashanthi Ratnakumar, Susannah Bloch, Simon Jordan, Simon Padley, Carole A. Ridge, Graham Robinson, Hasti Robbie, Joseph Barnett, Mario Silva, Sujal Desai, Richard W. Lee, Eric O. Aboagye & Anand Devaraj
Radium-223 in metastatic castration-resistant prostate cancer: whole-body diffusion-weighted magnetic resonance imaging scanning to assess response - JNCI Cancer Spectr. 2023 Oct 31;7(6):pkad077.
Parker C, Tunariu N, Tovey H, Alonzi R, Blackledge MD, Cook GJR, Chua S, Du Y, Hafeez S, Murray I, Padhani AR, Staffurth J, Tree A, Stidwill H, Finch J, Curcean A, Chatfield P, Perry S, Koh DM, Hall E.
Relative fat fraction of malignant bone lesions from breast cancer, prostate cancer and myeloma are significantly lower than normal bone marrow and shows excellent interobserver agreement. - Br J Radiol. 2023 Oct 31:20230240.
Castagnoli F, Donners R, Tunariu N, Messiou C, Koh DM.
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance - Nature. 2023 Oct 16.
Christina Guo, Adam Sharp, Bora Gurel, Mateus Crespo, Ines Figueiredo, Suneil Jain, Ursula Vogl, Jan Rekowski, Mahtab Rouhifard, Lewis Gallagher, Wei Yuan, Suzanne Carreira, Khobe Chandran, Alec Paschalis, Ilaria Colombo, Anastasios Stathis, Claudia Bertan, George Seed, Jane Goodall, Florence Raynaud, Ruth Ruddle, Karen E. Swales, Jason Malia, Denisa Bogdan, Crescens Tiu, Reece Caldwell, Caterina Aversa, Ana Ferreira, Antje Neeb, Nina Tunariu, Daniel Westaby, Juliet Carmichael, Maria de los Dolores Fenor de la Maza, Christina Yap, Ruth Matthews, Hannah Badham, Toby Prout, Alison Turner, Mona Parmar, Holly Tovey, Ruth Riisnaes, Penny Flohr, Jesus Gil, David Waugh, Shaun Decordova, Anna Schlag, Bianca Calì, Andrea Alimonti & Johann S. de Bono
Ravindhi Murphy, Gurvin Chander, Maria Martinez, Caroline Ward, Sairah R. Khan, Mitesh Naik, Tara Barwick, Eric Aboagye, Rohini Sharma
The Biomarker Toolkit — an evidence-based guideline to predict cancer biomarker success and guide development - BMC Med. 2023 Oct 4;21(1):383.
Katerina-Vanessa Savva, Michal Kawka, Bhamini Vadhwana, Rahul Penumaka, Imogen Patton, Komal Khan, Claire Perrott, Saranya Das, Maxime Giot, Stella Mavroveli, George B Hanna, Melody Zhifang Ni, Christopher J Peters
Olaparib and celarasertib (AZD6738) in patients with triple negative advanced breast cancer: results from Cohort E of the plasmaMATCH trial (CRUK/15/010) - Clin Cancer Res. 2023 Sep 29.
Ring A, Kilburn LS, Pearson A, Moretti L, Afshari-Mehr A, Wardley AM, Gurel B, Macpherson IR, Riisnaes R, Baird RD, Martin S, Roylance R, Johnson H, Ferreira A, Winter MC, Dunne K, Copson E, Hickish T, Burcombe R, Randle K, Serra V, Llop-Guevara A, Bliss JM, Turner NC.
The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer - J Clin Invest. 2023 Sep 26:e169200.
Adamson B, Brittain N, Walker L, Duncan R, Luzzi S, Rescigno P, Smith GR, McGill S, Burchmore RJ, Willmore E, Hickson I, Robson CN, Bogdan D, Jimenez-Vacas JM, Paschalis A, Welti J, Yuan W, McCracken SR, Heer R, Sharp A, de Bono J, Gaughan L.
Phase 1/2A trial of idroxioleic acid: first-in-class sphingolipid regulator and glioma cell autophagy inducer with antitumor activity in refractory glioma - Br J Cancer. 2023 Sep;129(5):811-818.
Lopez J, Lai-Kwon J, Molife R, Welsh L, Tunariu N, Roda D, Fernández-García P, Lladó V, McNicholl AG, Rosselló CA, Taylor RJ, Azaro A, Rodón J, Sludden J, Veal GJ, Plummer R, Urruticoechea A, Lahuerta A, Mujika K, Escribá PV. A.
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response - Nat Genet. 2023 Aug;55(8):1311-1323.
Philip Bland, Harry Saville, Patty T. Wai, Lucinda Curnow, Gareth Muirhead, Jadwiga Nieminuszczy, Nivedita Ravindran, Marie Beatrix John, Somaieh Hedayat, Holly E. Barker, James Wright, Lu Yu, Ioanna Mavrommati, Abigail Read, Barrie Peck, Mark Allen, Patrycja Gazinska, Helen N. Pemberton, Aditi Gulati, Sarah Nash, Farzana Noor, Naomi Guppy, Ioannis Roxanis, Guy Pratt, …Rachael Natrajan
Development and Validation of a New BAG-1L-Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer - Lab Invest. 2023 Aug 29;103(11):100245.
Neeb A, Figueiredo I, Gurel B, Nava Rodrigues D, Rekowski J, Riisnaes R, Ferreira A, Miranda S, Crespo M, Westaby D, de Los Dolores Fenor de La Maza M, Guo C, Carmichael J, Grochot R, Tunariu N, Cato ACB, Plymate SR, de Bono JS, Sharp A.
The value of baseline 18F-sodium fluoride and 18F-choline PET activity for identifying responders to radium-223 treatment in castration-resistant prostate cancer bone metastases - Eur Radiol. 2023 Aug 24.
Donners R, Tunariu N, Tovey H, Hall E, Chua S, Cook G, Du Y, Blackledge MD, Parker CC, Koh DM.
The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells - Nat Cancer. 2023 Aug;4(8):1102-1121.
Brina D, Ponzoni A, Troiani M, Calì B, Pasquini E, Attanasio G, Mosole S, Mirenda M, D'Ambrosio M, Colucci M, Guccini I, Revandkar A, Alajati A, Tebaldi T, Donzel D, Lauria F, Parhizgari N, Valdata A, Maddalena M, Calcinotto A, Bolis M, Rinaldi A, Barry S, Rüschoff JH, Sabbadin M, Sumanasuriya S, Crespo M, Sharp A, Yuan W, Grinu M, Boyle A, Miller C, Trotman L, Delaleu N, Fassan M, Moch H, Viero G, de Bono J, Alimonti A.
openFrame: A modular, sustainable, open microscopy platform with single-shot, dual-axis optical autofocus module providing high precision and long range of operation - J Microsc. 2023 Aug 24.
Jonathan Lightley, Sunil Kumar, M Q Lim, E Garcia, F Görlitz, Y Alexandrov, T Parrado, C Hollick, E Steele, K Roßmann, J Graham, J Broichhagen, I A McNeish, C A Roufosse, M A A Neil, Chris Dunsby, P M W French
Accelerating 4D image reconstruction magnetic resonance-guided radiotherapy - Phys Imaging Radiat Oncol. 2023 Aug 23.
Participatory evaluation of the process of co-producing resources for the public on data science and artificial intelligence - Res Involv Engagem. 2023 Aug 14;9(1):67.
Piotr Teodorowski, Kelly Gleason, Jonathan J. Gregory, Martha Martin, Reshma Punjabi, Suzanne Steer, Serdar Savasir, Pournamy Vema, Kabelo Murray, Helen Ward & Dorota Chapko
The clinical terrain of immunotherapies in heterogeneous pancreatic cancer: unravelling challenges and opportunities - J Pathol. 2023 Aug 7.
Melanie Herpels, Jun Ishihara, Anguraj Sadanandam
Handheld ISFET Lab-on-Chip detection of TMPRSS2-ERG and AR mRNA for prostate cancer prognostics - IEEE Sens Lett. 2023 Aug;7(8):1-4.
Joseph Broomfield, Melpomeni Kalofonou, Sylvia Franklin, Sue M Powell, Thomas Pataillot-Meakin, Nicolas Moser, Charlotte L Bevan, Pantelis Georgiou
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target - Nat Metab. 2023 Aug;5(8):1303-1318.
Johan Vande Voorde, Rory T. Steven, Arafath K. Najumudeen, Catriona A. Ford, Alex Dexter, Ariadna Gonzalez-Fernandez, Chelsea J. Nikula, Yuchen Xiang, Lauren Ford, Stefania Maneta Stavrakaki, Kathryn Gilroy, Lucas B. Zeiger, Kathryn Pennel, Phimmada Hatthakarnkul, Efstathios A. Elia, Ammar Nasif, Teresa Murta, Eftychios Manoli, Sam Mason, Michael Gillespie, Tamsin R. M. Lannagan, Nikola Vlahov, Rachel A. Ridgway, Colin Nixon, Alexander Raven, Megan Mills, Dimitris Athineos, Georgios Kanellos, Craig Nourse, David M. Gay, Mark Hughes, Amy Burton, Bin Yan, Katherine Sellers, Vincen Wu, Kobe De Ridder, Engy Shokry, Alejandro Huerta Uribe, William Clark, Graeme Clark, Kristina Kirschner, Bernard Thienpont, Vivian S. W. Li, Oliver D. K. Maddocks, Simon T. Barry, Richard J. A. Goodwin, James Kinross, Joanne Edwards, Mariia O. Yuneva, David Sumpton, Zoltan Takats, Andrew D. Campbell, Josephine Bunch & Owen J. Sansom
Role of procalcitonin in predicting complications of Kawasaki disease - Arch Dis Child. 2023 Jul 31;archdischild-2023-325787.
Kazuki Iio, Heather Hanna, Melina Beykou, Chris Gale, Jethro Adam Herberg
Classification of nucleic acid amplification on ISFET arrays using spectrogram-based neural networks - Comput Biol Med. 2023 Jul;161:107027.
Prateek Tripathi, Costanza Gulli, Joseph Broomfield, George Alexandrou, Melpomeni Kalofonou, Charlotte Bevan, Nicolas Moser, Pantelis Georgiou
Unbiased differential proteomic profiling between cancer-associated fibroblasts and cancer cell lines - J Proteomics. 2023 Jul 20;104973.
Rachel Lau, Lu Yu, Theodoros I Roumeliotis, Adam Stewart, Lisa Pickard, Ruth Riisanes, Bora Gurel, Johann S de Bono, Jyoti S Choudhary, Udai Banerji
Proteome-wide structural analysis identifies warhead- and coverage-specific biases in cysteine-focused chemoproteomics - Cell Chem Biol. 2023 Jul 20;30(7):828-838.e4.
Matthew E.H. White, Jesus Gil, Edward W. Tate
Clinical trial designs for evaluating and exploiting cancer evolution - Cancer Treat Rev. 2023 Jul;118:102583.
Alvaro H Ingles Garces, Nuria Porta, Trevor A Graham, Udai Banerji
The potential role of the microbiota in prostate cancer pathogenesis and treatment. - Nat Rev Urol. 2023 Jul 25.
Pernigoni N, Guo C, Gallagher L, Yuan W, Colucci M, Troiani M, Liu L, Maraccani L, Guccini I, Migliorini D, de Bono J, Alimonti A.
Critical role of antioxidant programs in enzalutamide-resistant prostate cancer - Oncogene. 2023 Jul;42(30):2347-2359.
Blatt EB, Parra K, Neeb A, Buroni L, Bogdan D, Yuan W, Gao Y, Gilbreath C, Paschalis A, Carreira S, DeBerardinis RJ, Mani RS, de Bono JS, Raj GV.
A Phase 1/2 trial of SRA737 (a Chk1 inhibitor) administered orally in patients with advanced cancer - Br J Cancer. 2023 Jul;129(1):38-45.
Rebecca Kristeleit, Ruth Plummer, Robert Jones, Louise Carter, Sarah Blagden, Debashis Sarker, Tobias Arkenau, Thomas R Jeffry Evans, Sarah Danson, Stefan N Symeonides, Gareth J Veal, Barbara J Klencke, Mark M Kowalski, Udai Banerji
Circulating Tumor Cell Cluster Sorting by Size and Asymmetry - Methods Mol Biol. 2023;2679:15-23.
Sam H Au
Dynamics and Molecular Interactions of GPI-Anchored CD59 - Toxins 2023, 15(7), 430.
Tomas B. Voisin, Emma C. Couves, Edward W. Tate and Doryen Bubeck
Cancer Loyalty Card Study (CLOCS): feasibility outcomes for an observational case-control study focusing on the patient interval in ovarian cancer - BMJ Open. 2023 Jun 14;13(6):e066022.
Hannah R Brewer, Marc Chadeau-Hyam, Eric Johnson, Sudha Sundar, James Flanagan, Yasemin Hirst
Immuno-PET Imaging of Tumour PD-L1 Expression in Glioblastoma - Cancers (Basel). 2023 Jun 9;15(12):3131.
Gitanjali Sharma, Marta C Braga, Chiara Da Pieve, Wojciech Szopa, Tatjana Starzetz, Karl H Plate, Wojciech Kaspera, Gabriela Kramer-Marek
Non-contrast CT synthesis using patch-based cycle-consistent generative adversarial network (Cycle-GAN) for radiomics and deep learning in the era of COVID-19 - Sci Rep. 2023 Jun 29;13(1):10568.
Reza Kalantar, Sumeet Hindocha, Benjamin Hunter, Bhupinder Sharma, Nasir Khan, Dow-Mu Koh, Merina Ahmed, Eric O. Aboagye, Richard W. Lee & Matthew D. Blackledge
The CDK7 inhibitor CT7001 (Samuraciclib) targets proliferation pathways to inhibit advanced prostate cancer - Br J Cancer. 2023 Jun;128(12):2326-2337.
Theodora A. Constantin, Anabel Varela-Carver, Kyle K. Greenland, Gilberto Serrano de Almeida, Ellen Olden, Lucy Penfold, Simon Ang, Alice Ormrod, Damien A. Leach, Chun-Fui Lai, Edward K. Ainscow, Ash K. Bahl, David Carling, Matthew J. Fuchter, Simak Ali & Charlotte L. Bevan
Is tumour volume an independent predictor of outcome after radical prostatectomy for high-risk prostate cancer? - Prostate Cancer Prostatic Dis. 2023 Jun;26(2):282-286.
Nicholas Raison, Pol Servian, Amit Patel, Ainkaran Santhirasekaram, Andrew Smith, Maidie Yeung, Josephine Lloyd, Ethna Mannion, Andrea Rockall, Hashim Ahmed & Mathias Winkler
Hannah R. Brewer, Qianhui Jiang, Sudha Sundar, Yasemin Hirst, James M. Flanagan
Distributed large-scale graph processing on FPGAs - J Big Data. 2023;10(1):95.
Amin Sahebi, Marco Barbone, Marco Procaccini, Wayne Luk, Georgi Gaydadjiev, Roberto Giorgi
Advanced MR Techniques for Preoperative Glioma Characterization: Part 1 & Part 2 - J Magn Reson Imaging. 2023 Jun;57(6):1676-1695
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Capillary-Scale Hydrogel Microchannel Networks by Wire Templating - Small 2023 Jun 2;e2301163.
Shusei Kawara, Brian Cunningham, James Bezer, Neelima Kc, Jingwen Zhu, Meng-Xing Tang, Jun Ishihara, James J Choi, Sam H Au
A YOLOv5-based network for the detection of a diffuse reflectance spectroscopy probe to aid surgical guidance in gastrointestinal cancer surgery - Int J Comput Assist Radiol Surg. 2023 Jun 8.
Ioannis Gkouzionis, Yican Zhong, Scarlet Nazarian, Ara Darzi, Nisha Patel, Christopher J Peters, Daniel S Elson
Triaxial accelerometer-measured physical activity and functional behaviours among people with High Grade Glioma: The BrainWear Study - PLoS One. 2023 May 24;18(5):e0285399.
Seema Dadhania, Lillie Pakzad-Shahabi, Sanjay Mistry, Matt Williams
Imaging in metastatic breast cancer, CT, PET/CT, MRI, WB-DWI, CCA: review and new perspectives - Cancer Imaging. 2023 May 31;23(1):53.
Lother D, Robert M, Elwood E, Smith S, Tunariu N, Johnston SRD, Parton M, Bhaludin B, Millard T, Downey K, Sharma B.
Active mesh and neural network pipeline for cell aggregate segmentation - Biophys J. 2023 May 2;122(9):1586-1599.
Matthew B Smith, Hugh Sparks, Jorge Almagro, Agathe Chaigne, Axel Behrens, Chris Dunsby, Guillaume Salbreux
Pathobionts in the tumour microbiota predict survival following resection for colorectal cancer - Microbiome. 2023 May 8;11(1):100.
James L. Alexander, Joram M. Posma, Alasdair Scott, Liam Poynter, Sam E. Mason, M. Luisa Doria, Lili Herendi, Lauren Roberts, Julie A. K. McDonald, Simon Cameron, David J. Hughes, Vaclav Liska, Simona Susova, Pavel Soucek, Verena Horneffer-van der Sluis, Maria Gomez-Romero, Matthew R. Lewis, Lesley Hoyles, Andrew Woolston, David Cunningham, Ara Darzi, Marco Gerlinger, Robert Goldin, Zoltan Takats, Julian R. Marchesi, Julian Teare & James Kinross
Asymmetric Dimethylation of Ribosomal S6 Kinase 2 Regulates Its Cellular Localisation and Pro-Survival Function - Int J Mol Sci. 2023 May 15;24(10):8806.
Mahmoud I Khalil, Heba M Ismail, Ganna Panasyuk, Anna Bdzhola, Valeriy Filonenko, Ivan Gout, Olivier E Pardo
Enhanced Sestrin expression through Tanshinone 2A treatment improves PI3K-dependent inhibition of glioma growth - Cell Death Discov. 2023 May 19;9(1):172.
Judith Schaf, Sonia Shinhmar, Qingyu Zeng, Olivier E. Pardo, Philip Beesley, Nelofer Syed & Robin S. B. Williams
REFINE-Lung implements a novel multi-arm randomised trial design to address possible immunotherapy overtreatment - Lancet Oncol. 2023 May;24(5):e219-e227.
Ehsan Ghorani, Matteo Quartagno, Fiona Blackhall, Duncan C Gilbert, Mary O'Brien, Christian Ottensmeier, Elena Pizzo, James Spicer, Alex Williams, Philip Badman, Mahesh K B Parmar, Michael J Seckl; REFINE-Lung Investigators
Germline ATM Mutations Detected by Somatic DNA Sequencing in Lethal Prostate Cancer - Eur Urol Open Sci. 2023 May 2;52:72-78. doi: 10.1016/j.euros.2023.04.003.
Rafael Grochot, Suzanne Carreira, Susana Miranda, Ines Figueiredo, Claudia Bertan, Jan Rekowski, Wei Yuan, Ana Ferreira, Ruth Riisnaes, Antje Neeb, Bora Gurel, Maria de Los Dolores Fenor de la Maza, Christina Guo, Juliet Carmichael, Daniel Westaby, Joaquin Mateo, Adam Sharp, Terri P McVeigh, Johann De Bono
A palmitoyl transferase chemical genetic system to map ZDHHC-specific S-acylation - BioRxiv 2023.04.18.537386.
Cory A. Ocasio, Marc P. Baggelaar, James Sipthorp, Ana Losada de la Lastra, Jana Volarić, Christelle Soudy, Elisabeth M. Storck, Susana A. Palma-Duran, James I. MacRae, Goran Tomic, Lotte Carr, Julian Downward, Ulrike S. Eggert, Edward W. Tate
A Transgender Patient with Prostate Cancer: Lessons Learnt - Eur Urol. 2023 Apr;83(4):379-380.
Khobe Chandran, Rafael Grochot, Maria de Los Dolores Fenor De La Maza, Wei Yuan, Bora Gurel, Susana Miranda, Alec Paschalis, Ruth Riisnaes, Ines Figueiredo, Denisa Bogdan, Adam Sharp, Suzanne Carreira, Johann S de Bono
Antibodies against endogenous retroviruses promote lung cancer immunotherapy - Nature. 2023 Apr;616(7957):563-573.
Kevin W. Ng, Jesse Boumelha, Katey S. S. Enfield, Jorge Almagro, Hongui Cha, Oriol Pich, Takahiro Karasaki, David A. Moore, Roberto Salgado, Monica Sivakumar, George Young, Miriam Molina-Arcas, Sophie de Carné Trécesson, Panayiotis Anastasiou, Annika Fendler, Lewis Au, Scott T. C. Shepherd, Carlos Martínez-Ruiz, Clare Puttick, James R. M. Black, Thomas B. K. Watkins, Hyemin Kim, Seohee Shim, Nikhil Faulkner, Jan Attig, Selvaraju Veeriah, Neil Magno, Sophia Ward, Alexander M. Frankell, Maise Al Bakir, Emilia L. Lim, Mark S. Hill, Gareth A. Wilson, Daniel E. Cook, Nicolai J. Birkbak, Axel Behrens, Nadia Yousaf, Sanjay Popat, Allan Hackshaw, TRACERx Consortium, CAPTURE Consortium, Crispin T. Hiley, Kevin Litchfield, Nicholas McGranahan, Mariam Jamal-Hanjani, James Larkin, Se-Hoon Lee, Samra Turajlic, Charles Swanton, Julian Downward & George Kassiotis
Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma - Hepatol Int. 2023 Apr 1.
Mathew Vithayathil, Antonio D’Alessio, Claudia Angela Maria Fulgenzi, Naoshi Nishida, Martin Schönlein, Johann von Felden, Kornelius Schulze, Henning Wege, Anwaar Saeed, Brooke Wietharn, Hannah Hildebrand, Linda Wu, Celina Ang, Thomas U. Marron, Arndt Weinmann, Peter R. Galle, Dominik Bettinger, Bertram Bengsch, Arndt Vogel, Lorenz Balcar, Bernhard Scheiner, Pei-Chang Lee, Yi-Hsiang Huang, Suneetha Amara, Mahvish Muzaffar, Abdul Rafeh Naqash, Antonella Cammarota, Valentina Zanuso, Tiziana Pressiani, Matthias Pinter, Alessio Cortellini, Masatoshi Kudo, Lorenza Rimassa, David J. Pinato & Rohini Sharma
Rapid short-pulses of focused ultrasound and microbubbles deliver a range of agent sizes to the brain - Sci Rep. 2023 Apr 28;13(1):6963.
William Lim Kee Chang, Tiffany G Chan, Federica Raguseo, Aishwarya Mishra, Dani Chattenton, Rafael T M de Rosales, Nicholas J Long, Sophie V Morse
Acceleration-Based Kalman Tracking for Super-Resolution Ultrasound Imaging in vivo - Arxiv
Biao Huang, Jipeng Yan, Megan Morris, Victoria Sinnett, Navita Somaiah, Meng-Xing Tang
What is so Special About Digital Health in Cancer? - Clin Oncol (R Coll Radiol). 2023 Mar;35(3):147-149.
S Dadhania, M Williams
Progression patterns and therapeutic sequencing following immune checkpoint inhibition for hepatocellular carcinoma: An international observational study - Liver Int. 2023 Mar;43(3):695-707
B7-H3 as a Therapeutic Target in Advanced Prostate Cancer - Eur Urol. 2023 Mar;83(3):224-238.
Christina Guo, Ines Figueiredo, Bora Gurel, Antje Neeb, George Seed, Mateus Crespo, Suzanne Carreira, Jan Rekowski, Lorenzo Buroni, Jon Welti, Denisa Bogdan, Lewis Gallagher, Adam Sharp, Maria D Fenor de la Maza, Pasquale Rescigno, Daniel Westaby, Khobe Chandran, Ruth Riisnaes, Ana Ferreira, Susana Miranda, Bianca Calì, Andrea Alimonti, Silvia Bressan, Alana H T Nguyen, Michael M Shen, Jessica E Hawley, Aleksandar Obradovic, Charles G Drake, Claudia Bertan, Chloe Baker, Nina Tunariu, Wei Yuan, Johann S de Bono
Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting - Adv Mater. 2023 Mar 11;e2300413.
Adam Creamer, Alessandra Lo Fiego, Alice Agliano, Lino Prados-Martin, Håkon Høgset, Adrian Najer, Daniel A. Richards, Jonathan P. Wojciechowski, James E. J. Foote, Nayoung Kim, Amy Monahan, Jiaqing Tang, André Shamsabadi, Léa N. C. Rochet, Ioanna A. Thanasi, Laura R. de la Ballina, Charlotte L. Rapley, Stephen Turnock, Elizabeth A. Love, Laurence Bugeon, Margaret J. Dallman, Martin Heeney, Gabriela Kramer-Marek, Vijay Chudasama, Federico Fenaroli, Molly M. Stevens
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer. - Cancer Cell. 2023 Mar 13;41(3):602-619.e11.
Bancaro N, Calì B, Troiani M, Elia AR, Arzola RA, Attanasio G, Lai P, Crespo M, Gurel B, Pereira R, Guo C, Mosole S, Brina D, D'Ambrosio M, Pasquini E, Spataro C, Zagato E, Rinaldi A, Pedotti M, Di Lascio S, Meani F, Montopoli M, Ferrari M, Gallina A, Varani L, Pereira Mestre R, Bolis M, Gillessen Sommer S, de Bono J, Calcinotto A, Alimonti A.
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth - Oncogene. 2023 Mar;42(12):926-937.
Emma Scott, Kirsty Hodgson, Beatriz Calle, Helen Turner, Kathleen Cheung, Abel Bermudez, Fernando Jose Garcia Marques, Hayley Pye, Edward Christopher Yo, Khirul Islam, Htoo Zarni Oo, Urszula L. McClurg, Laura Wilson, Huw Thomas, Fiona M. Frame, Margarita Orozco-Moreno, Kayla Bastian, Hector M. Arredondo, Chloe Roustan, Melissa Anne Gray, Lois Kelly, Aaron Tolson, Ellie Mellor, Gerald Hysenaj, Emily Archer Goode, Rebecca Garnham, Adam Duxfield, Susan Heavey, Urszula Stopka-Farooqui, Aiman Haider, Alex Freeman, Saurabh Singh, Edward W. Johnston, Shonit Punwani, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna Harries, Denisa Bogdan, Daniel Westaby, Gemma Fowler, Penny Flohr, Wei Yuan, Adam Sharp, Johann de Bono, Norman J. Maitland, Simon Wisnovsky, Carolyn R. Bertozzi, Rakesh Heer, Ramon Hurtado Guerrero, Mads Daugaard, Janne Leivo, Hayley Whitaker, Sharon Pitteri, Ning Wang, David J. Elliott, Benjamin Schumann & Jennifer Munkley
PETAL protocol: a phase Ib study of pembrolizumab after transarterial chemoembolization in hepatocellular carcinoma - Future Oncol. 2023 Mar;19(7):499-507. doi: 10.2217/fon-2022-0916.
Petros Fessas, Bernhard Scheiner, Antonio D'Alessio, Claudia A M Fulgenzi, James Korolewicz, Caroline Ward, Paul Tait, Robert Thomas, Alessio Cortellini, Rohini Sharma, David J Pinato
Apoptosis-modulatory miR-361-3p as a novel treatment target in endocrine-responsive and endocrine-resistant breast cancer - J Endocrinol. 2023 Feb 11;256(3):e220229.
J N Zamarbide Losada, E Sulpice, S Combe, G S Almeida, D A Leach, J Choo, L Protopapa, M P Hamilton, S McGuire, X Gidrol, C L Bevan, C E Fletcher
Victoria I. Cushing, Adrian F. Koh, Junjie Feng, Kaste T. Jurgaityte, Ash K. Bahl, Simak Ali, Abhay Kotecha, Basil J. Greber
Association Between Purchase of Over-the-Counter Medications and Ovarian Cancer Diagnosis in the Cancer Loyalty Card Study (CLOCS): Observational Case-Control Study - JMIR Public Health Surveill. 2023 Jan 26;9:e41762.
Hannah R Brewer, Yasemin Hirst, Marc Chadeau-Hyam, Eric Johnson, Sudha Sundar, James M Flanagan
Adaptive resistance is not responsible for long-term drug resistance in a cellular model of triple negative breast cancer - Gene. 2023 Jan 20;850:146930.
Uttom Kumar, Marcos Castellanos-Uribe, Sean T May, Ernesto Yagüe
H3K4me3 mediates uterine leiomyoma pathogenesis via neuronal processes, synapsis components, proliferation, and Wnt/β-catenin and TGF-β pathways - Reprod Biol Endocrinol. 2023 Jan 26;21(1):9.
María Cristina Carbajo-García, Elena Juarez-Barber, Marina Segura-Benítez, Amparo Faus, Alexandra Trelis, Javier Monleón, Greta Carmona-Antoñanzas, Antonio Pellicer, James M Flanagan, Hortensia Ferrero
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