Converging on Cancer – Infrastructure: Microfabrication & Organoid Facilities

Please join us for a special seminar on Thursday 29th September, from 15.00-16.00, to hear about the Microfabrication & Prototyping Facility and the Human Organoid Facility & Biobank.


  • Are you using biological models such as single cell suspensions, co-cultures, 3D patient-derived models (e.g, organoid, organ-on-chip, explant) or even working in vivo?
  • Are you interested in the design of devices to detect, inform, dispense, analyse or monitor biological processes?
  • Do you want to develop prototypes for MedTech or biomarker platforms?

 

The Cancer Research UK Convergence Science Centre supports infrastructure capabilities to address bottlenecks and facilitate translational research.

 

It is our pleasure to introduce to you two of our facilities: The Microfabrication and Prototyping Facility and the Human Organoid Facility and Biobank.

 

Please join us for a special seminar on Thursday 29th September, from 15.00-16.00, to learn more about what these facilities can do for your research and hearing from our experts Dr Sam Au, Dr Florent Seichepine and Dr Simon Tupin (Microfabrication & Prototyping) and Professor Axel Behrens and Dr Sudeep Bhushal (Human Organoid).

 

Contact us at icr-imperial-convergence.centre@imperial.ac.uk to access the seminar

 

Please note: This webinar is exclusively available to colleagues from the Institute of Cancer Research, the Royal Marsden, Imperial and Imperial College Healthcare.

 

The Converging on Cancer seminar series is brought to you by the Cancer Research UK Convergence Science Centre at Imperial College London and The Institute of Cancer Research, London. Researchers across the two organisations will discuss key challenges facing cancer research and opportunities for new convergence science approaches to address these. Hosted by the Convergence Science Centre's Scientific Director Professor Axel Behrens, the series aims to support the Centre's mission to facilitate collaboration between traditionally separate and distinct disciplines to address challenges in cancer and bring pioneering treatments to cancer patients faster.

 

The Microfabrication & Prototyping Facility: Dr Sam Au, Dr Florent Seichepine and Dr Simon Tupin – Department of Bioengineering, Imperial College London

 

Moving past the well plate: Microfabrication made easy for organoids and convergence cancer science

 

Microscale platforms including lab-on-chip, organ-on-chip and tumour-on-chip devices may provide superior physiological environments for studying cancer biology and developing therapies. In this talk, the staff of the CRUK Microfabrication & Prototyping Facility will briefly introduce some case studies where microfabrication techniques have been used effectively in the areas of organoids, organ-on-chip devices and interfacing with animal models. We will then highlight the equipment, expertise and technical support on offer and how easily and affordable it is for your groups to access the Facility.

 

Sam Au is a senior lecturer in Bioengineering at Imperial College whose group specializes in the development of novel microfluidic devices for applications in the cancer space. He is the founding director of the CRUK Convergence Science Centre-funded Microfabrication & Prototyping Facility as well as the MRes in Cancer Technology programme, both of which are jointly developed with the Institute of Cancer Research.

 

Florent Seichepine is bionanofabrication and Clean Room Manager in the department of Bioengineering. He oversees the tools for microfabrication in the department and oversee the technical collaboration with the other technology platforms. He earned his PhD on the manipulation of carbon nanotube and nanowires for microelectronics and cells interfacing. He since has been focussing on developing state-of-the-art technologies for application in medicine, biology, and life science.

 

The Human Organoid Facility & Biobank: Dr Sudeep Bhushal – CRUK Convergence Science Centre

 

3D organoid culture : A new window into development and disease

 

Organoids are in-vitro 3D cellular models derived from primary tissue or stem cells that faithfully recapitulate key elements of the tissue of origin. Organoids are revolutionizing in vitro cell culture as they are accessible, physiologically relevant, and stable system for extended cultivation. However, there are several factors that still restricting their widespread application as novel models for cancer research. In this talk, I will elaborate on the CRUK Organoid Facility and Biobank’s aim to develop new methodologies and technologies to maximise the potential of organoids for cancer research via interdisciplinary, cross-institution, collaborations.

 

Sudeep is a Higher Scientific Officer at ICR as part of CRUK Convergence Science Centre. He is an expert in organoid derivation from tissues and provides on-site training for scientists and clinicians using organoid system for the first time.


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